Publications with undergraduate and postbac co-authors (in bold)
Gurley, N.J., Szymanski, R.A., Dowen, R.H., Butcher, T.A., Ishiyama, N. and Peifer, M. (2023). Exploring the evolution and function of Canoe’s intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis. PLoS One 18: e0289224.
Schmidt, A., Finegan, T., Häring, M., Kong, D., Fletcher, A.G., Alam, Z., Grosshans, J., Wolf, F., and Peifer, M. (2023). Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins. Molecular Biology of the Cell 34:ar81. doi: 10.1091/mbc.E23-03-0077.
Perez-Vale, K.Z.*, Yow, K,D.*, Gurley, N. J., Greene, M., and Peifer, M. (2023) Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms. Molecular Biology of the Cell 34: ar7. doi.org/10.1091/mbc.E22-05-0176
Yu-Kemp, H.-C., Szymanski, R.A., Cortes, D.B., Gadda, N.C., Lillich, M.I., Maddox, A.S., and Peifer, M. (2021) Micron-scale supramolecular myosin arrays help mediate cytoskeletal assembly at mature adherens junctions. Journal of Cell Biology 221: e202103074.
Rogers, E.M., Allred, S.C., and Peifer, M. (2021). Abelson kinase’s intrinsically disordered region plays essential roles in protein function and protein stability. Cell Communication and Signaling 9:27. doi: 10.1186/s12964-020-00703-w.
Spracklen, A.J., Thornton-Kolbe, E.M., Bonner, A,N., Florea, A., Compton, P.J., Fernandez-Gonzalez,R., and Peifer, M. (2019). The Crk adapter protein is essential for Drosophila embryogenesis where it regulates multiple actin-dependent morphogenic events. Molecular Biology of the Cell 30, 2399-2421.
Manning, L.A., Perez-Vale, K.Z., Schaefer, K.N., Sewell, M.T., Peifer, M. (2019). The Drosophila Afadin and ZO-1 homologs Canoe and Polychaetoid act in parallel to maintain epithelial integrity when challenged by adherens junction remodeling. Molecular Biology of the Cell 30, 1938-1960.
Schaefer, K.N., Bonello, T.T., Zhang, S., Williams, C.E., Roberts, D.M., McKay, D.J, and Peifer, M. (2018). Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo. PLoS Genetics doi.org/10.1371/journal.pgen.1007339.
Poulton, J.S., Cuningham, J.C., and Peifer, M. (2017). Centrosome and Spindle Assembly Checkpoint Loss Leads to Neural Apoptosis and Reduced Brain Size. Journal of Cell Biology 216, 1255-1265.
Pronobis, M.I., Deuitch, N., Posham, V., Mimori-Kiyosue, Y. and Peifer, M. (2017). Reconstituting regulation of the canonical Wnt pathway by engineering a minimal βcatenin destruction machine. Molecular Biology of the Cell 28, 41-53.
Pronobis, M.I., Deuitch, N., and Peifer, M. (2016). The Miraprep: A protocol that uses a Miniprep kit and provides Maxiprep yields. PLoS One 11, e0160509.
Rogers, E.M., Spracklen, A.J., Bilancia, C.G., Sumigray, K.D. Allred, S.C., Nowotarski, S.N., Schaefer, K. N., Ritchie, B.J., and Peifer, M. (2016). Abelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis. Molecular Biology of the Cell 27, 2613-2631
Poulton, J.S., Cuningham, J.C., and Peifer, M. (2014). Acentrosomal Drosophila epithelial cells exhibit abnormal cell division, leading to cell death and compensatory proliferation. Developmental Cell 30:731-45.
Nowotarski, S.H., McKeon, N., Moser, R.J., and Peifer, M. (2014). The actin regulators Enabled and Diaphanous direct distinct protrusive behaviors in different tissues during Drosophila development. Molecular Biology of the Cell 25:3147-65.
Poulton, J.S., Mu, F.W., Roberts, D.M., and Peifer, M. (2013). APC2 and Axin promote mitotic fidelity by facilitating centrosome separation and cytoskeletal regulation. Development 140, 4226-4236
Roberts,D.M., Pronobis, M.I., Alexandre, K.M., Rogers, G.C., Schneider, D.E., Jung, K-C., Poulton, J.S., McKay, D. J., and Peifer, M. (2012) Defining components of the ßcatenin destruction complex and exploring its regulation and mechanisms of action during development. PLoS One 7: e31284.
Roberts,D.M., Pronobis, M.I., Poulton, J.S., Kane, E.G., and Peifer, M. (2012) Regulation of Wnt signaling by the tumor suppressor APC does not require ability to enter the nucleus nor a particular cytoplasmic localization. Molecular Biology of the Cell, 23, 2041-56.
Roberts,D.M., Pronobis, M.I., Poulton, J.S., Waldmann, J.D., Stephenson, E.M., Hanna, S., and Peifer, M. (2011). Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling. Molecular Biology of the Cell 22:1845-63.
Roeth, J.F., Sawyer, J.K., Wilner, D.A., and Peifer, M. (2009). Rab11 Helps Maintain Apical Crumbs and Adherens Junctions in the Drosophila Embryonic Ectoderm. PLoS One 4, e7634.
Gates, J., ,Nowotarski,S.H., Yin, H., Mahaffey, J.P., Bridges, T., Herrera,C., Homem,C.C.F., Janody, F., Montell, D.J.and Peifer,M. (2009) Enabled and Capping protein play important roles in shaping cell behavior during Drosophila oogenesis. Developmental Biology 333, 90-107.
Stevens, T L., Rogers, E M., Koontz, L. M. , Fox, D. T., Homem, C. C.F., Nowotarski, S. H., Artabazon, N. B., and Peifer, M. (2007). Using Bcr-Abl to examine mechanisms by which Abl kinase regulates morphogenesis in Drosophila. Molecular Biology of the Cell 19, 378-393.
Gates, J., Mahaffey, J.P., Rogers, S.L., Emerson, M., Rogers, E.M., Sottile, S.L., Van Vactor, D., Gertler, F.B., and Peifer, M. (2007). Enabled plays key roles in Embryonic Epithelial Morphogenesis in Drosophila. Development 134, 2027-2039.
McCartney, B.M., Price, M.H., Webb, R., , Hayden, M.A., Holot, L., Zhou, M, Bejsovec, A., and Peifer, M. (2006). Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila. Development 133, 2407-2418.
Price, M.H., Roberts, D.M., McCartney, B.M., Jezuit, E., and Peifer, M. (2006). Cytoskeletal dynamics and cell signaling during planar polarity establishment in the Drosophila embryonic denticle. Journal of Cell Science 119: 403-415.
Fox, D.T., Homem, C.C.F., Myster, S.H., Wang, F., Bain, E.E., and Peifer, M. (2005). Rho1 Regulates Drosophila Adherens Junctions Independently of p120ctn. Development, 132, 4819-4831.
Myster, S.H., Wang, F., Cavallo, R., Christian, W., Bhotika, S., Anderson, C.T., and Peifer, M. (2004). Genetic and bioinformatic analysis of 41C and the 2R heterochromatin of Drosophila melanogaster: A window on the heterochromatin-euchromatin junction. Genetics 166, 807-22.
Myster, S.H.,, Cavallo, R., Anderson, C.T., Fox, D.T.. and Peifer, M. (2003). Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component. Journal of Cell Biology160 433-449.
Akong, K., Grevengoed, E.E., Price, M.H., McCartney, B.M., Hayden, M.A., DeNofrio, J.C., and Peifer, M. (2002). Drosophila APC2 and APC1 play overlapping roles in Wingless signaling in the embryo and imaginal discs. Developmental Biology 250, 91-100.
Loureiro, J.J., Akong, K., Cayirlioglu, P., Baltus, A.E., DiAntonio, A., and Peifer, M. (2001) Activated Armadillo/ß-catenin does not play a general role in cell migration and process extension in Drosophila. Developmental Biology 235: 33-44.
McCartney, B., Dierick, H.A., Kirkpatrick, C., Moline, M.M., Baas, A., Peifer, M., and Bejsovec, A. Drosophila APC2 is a cytoskeletally-associated protein that regulates Wingless signaling in the embryonic epidermis. Journal of Cell Biology 146, 1303-1318.
Cox, R.T., Pai,L.-M., Miller, J.R., Orsulic, S.,Stein,J., McCormick, C.A., Audeh, Y., Wang, W., Moon, R.T., and Peifer, M. (1999). Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own. Development 126, 1327-1335.
Cox, R.T., Pai,L.-M., Kirkpatrick, C., Stein, J., and Peifer, M. (1999). Roles of the C-terminus of Armadillo in Wingless signaling in Drosophila . Genetics,153, 319-332.
Pai, L.-M., Kirkpatrick, C., Blanton, J., Oda, H., Takeichi, M., and Peifer, M. (1996). alpha-catenin and DE-cadherin occupy distinct binding sites on Drosophila Armadillo that differ substantially in size. J. Biol. Chem. 271, 32411-32420.
Rauskolb, C., Smith, K., Peifer, M., and Wieschaus, E. (1995). extradenticle determines segmental identities throughout Drosophila development. Development 121, 3663-3673.
Peifer, M., Pai, L.-M., and Casey, M. (1994). Phosphorylation of the Drosophila adhesive junction protein Armadillo: roles for Wingless signal and Zeste white-3 kinase. Dev. Biol. 166, 543-556.
Peifer, M., Sweeton, D., Casey, M., and Wieschaus, E. (1994). wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo. Development 120, 369-380.
