Rachel Szymanski


Background & Contact Information

Position Postbac student (2020 – Present)
Education: BS Genetics NC State 2020
Email: raszyman@email.unc.edu


Research Information

Epithelial cells assemble specialized actomyosin structures at E-Cadherin-based cell-cell junctions, and the force exerted drives cell shape change during morphogenesis.  The mechanisms used to build this supramolecular actomyosin structure remain unclear. We are using ZO-knockdown MDCK cells, which assemble a robust, polarized and highly organized actomyosin cytoskeleton at the zonula adherens, and combined genetic and pharmacological approaches with super-resolution microscopy to define molecular machines required.


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